Educational Info.
  

Nutritional Influences on
Muscular Development and Fat Metabolism
by J.E. Grogan for Show Feeds, Inc.

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Thyroid Hormones:
The thyroid plays a major role in controlling energy expenditure and determining the basal metabolic rate (BMR) - the resting rate at which calories are burned for energy. The thyroid hormones divert calories away from storage as fat so they are more easily used for energy. The thyroid is also critically important for the liberation and metabolism of stored fat.

As in many "activating" processes, one thyroid hormone is a catalyst for the other. Thyroxine (T4), the thyroid hormone released into the blood, is converted to triiodothyronine (T3) - the active thyroid hormone. T3 is the hormone that strongly activates fat metabolism.

The thyroid requires more than just iodine to function optimally. The vitamins A, B-2, C,E; the minerals potassium, magnesium, copper, zinc; the amino acid tyrosine; and possibly the trace element rubidium are all involved in healthy thyroid function.

It is also well known that carbohydrates can stimulate the conversion of T-4 to T-3. If the carbohydrate content of the diet is too low this conversion can be depressed.

The activation of thyroid hormone production is also dependent on the activity of a healthy pituitary gland. The anterior pituitary releases the hormone TSH to stimulate thyroid hormone synthesis. Inadequate thyroid function can also depress liver function where a large part of fat metabolism is activated.

Optimal thyroid function and it's fat mobilizing effects are dependent on a precise balance of a variety of factors. An over stimulation of thyroid activity can actually decrease lean muscle mass and cause a breakdown of body protein. This can rapidly deplete nutritional reserves and cause a major drop in overall health status.

Insulin:
Insulin is a hormone produced by the beta cells of the islets of langerhans in the pancreas. Insulin's chief functions are the regulation of carbohydrate and fat metabolism and the stimulation of amino acid and sugar uptake by the cells.

By increasing the transport of sugar into the cells blood, sugar tends to drop. This increases the formation of glycogen or stored sugar in the muscles. Insulin also increases cellular uptake of amino acids. This increases protein synthesis and minimizes the use of amino acids for energy production; which is very inefficient metabolically. Insulin, by increasing amino acid uptake inhibits the breakdown of lean muscle mass and helps to maintain the integrity of the body's chief calorie burning tissue, which is muscle tissue. Insulin can enhance functional thyroid status which can increase fat burning capabilities through the thyroid hormone T-3.

For optimal benefits insulin should stay in a very narrow range or level in the blood. Insulin as important as it is for sugar and amino acid uptake by the cells is a two-edged metabolic sword in any fat burning or metabolizing program. Healthy levels of insulin stabilize lean mass (muscle) and minimize fat production (lipogenesis). However, an overabundance of/or an over stimulation of insulin release can increase fat production markedly and very quickly. This results in a lowered lean to fat ratio because of the increase in body fat.

Stabilizing carbohydrates in the diet with adequate high quality proteins and fatty acids minimize the risks of an over release of insulin and it's subsequent fat producing properties. (this is especially important in non-ruminants).

Also, the use of nutrient insulin potentiators can minimize cellular over exposures to insulin to protect lean mass and minimize fat production.

Even though fat cells cannot be converted to muscle, their component fatty acids can be utilized for energy purposes and the fat cell itself can shrink to extremely low volumes. In part, the benefits of nutrition insulin potentiators activate these fat burning, fat-shrinking properties.

Growth Hormone:
Growth hormone (GH) or somatotropin is one of the best publicized muscle builders and fat burners. Growth hormone promotes the growth of cells and tissues by stimulating protein synthesis due to:

  1. Increased amino acid transport into the cells.

  2. Stimulation of RNA synthesis.

It also stimulates the release of fat for the production of energy. GH has the ability to increase the rate of fat breakdown (lipolysis) and inhibit the formation of new fat (lipogenesis). Growth hormone is formed in and released from the anterior pituitary. Physical exercise, sleep, caloric restriction, low blood sugar and certain amino acids can stimulate the release of growth hormone.

Growth hormone's primary synergists are insulin, testosterone and the minerals magnesium, zinc and potassium. The primary antagonist to growth hormone is the stress hormone cortisol produced by the adrenals in response to any physiologically stressful event.

Since GH is released by the anterior pituitary - healthy pituitary function is prerequisite to optimal GH release. Adequate high biological dietary proteins, stabilized carbohydrates, essential fatty acids and activated nutritional cofactors, including protected amino acids, glandular protein materials and certain phyto compounds can help achieve optimal GH release and its muscle building and fat burning qualities by contributing to the overall health of the pituitary.

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